Places like Loews or Home Depot it's a corporate decision to close - they're afraid of being sued by employees, and it likely is in a mandatory evacuation zone.
Even the McDonalds near my place was closed last night, pretty early too. Same deal. Little Ceasars was open though - I'm eating shitty leftover pizza right now!
My job on the other hand tried to spin working from home on Friday as "Because we're very concerned about our employees." - of course they only became very concerned shortly after Pinellas issued mandatory evacuations for Friday.